Zhang Ming-jie
2012
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Journal
Chemistry & Bioengineering
Abstract
In this paper,(S)-1-ethyl-2-aminomethylpyrrolidine was synthesized using L-proline as the starting material through N,O-diethylation,ammonolysis,and reduction by NaBH4-I2.This method was simple in operation with good safety,the reactants were easy to obtain and economically inexpensive,so it was more suitable for industrial production.