O. Nurkenov, S. Fazylov, A. Arinova
Nov 14, 2013
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Journal
Russian Journal of General Chemistry
Abstract
A possibility of nucleophilic substitution of the fluorine atom in 4-fluorobenzaldehyde with amines (morpholine, piperidine or cytisine) under convection heating and microwave irradiation was shown. Reactions of 4-morpholinyl- and 4-piperidinylbenzaldehyde with hydrazides of isonicotinic and salicylic acids afford the corresponding hydrazones. The structure of the synthesized compounds was confirmed by IR, 1H NMR spectroscopy, mass spectrometry, and X-ray analysis data.