A. Gangjee, K. Ohemeng
Jul 1, 1985
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0
Influential Citations
8
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
Condensation of 2,6-diamino-4-hydroxypyrimidine with 1-benzoyl-1,2,3,6-tetrahydropyrimidine-5-carboxal-dehyde (4) afforded a mixture of angular and linear tricyclic tetrahydropyrimidonaphthyridines. Separation of the mixture was affected by fractional precipitation. Condensation of 2,4,6-triaminopyrimidine with 1-benzoyl-4-chloro-1,2,3,6-tetrahydropyridine (5) was regiospecific and afforded only the substituted angular tetra-hydropyrimido[4,5-c][2,7]naphthyridine (2). The vinyl aldehyde 4 and the chlorovinyl aldehyde 5 were prepared by modifications of literature procedures.