P. Vedsø, P. Olesen, T. Hoeg-Jensen
Apr 1, 2004
Citations
0
Influential Citations
24
Citations
Journal
Synlett
Abstract
Sulfonyl chlorides of phenylboronic esters have been made available by selective lithiation of bromo N-methyl-di-ethanolamine phenylboronates to give lithium sulfinyl phenylboronates as intermediates. Oxidations with N-chlorosuccinimide give the target sulfonyl chlorides, which may be isolated or used in situ for further reactions. The novel reagents are useful in preparation of among other sulfonamides of phenylboronic acids for use in Pd(0) catalysed cross-couplings. They also hold potential as carbohydrate binders with physiological pK a .