P. Shao, Feng Ye
May 26, 2008
Citations
0
Influential Citations
8
Citations
Journal
Tetrahedron Letters
Abstract
Abstract A stereoselective approach to the synthesis of cis - and trans -3-fluoro-1-phenylcyclobutylamine has been developed. Excellent stereoselectivity was obtained by the reduction of the appropriately substituted cyclobutanone to give either cis- or trans-isomers of 3-hydroxyl-1-phenylcyclobutylamine, which was stereoselectively converted to the 3-fluoro derivative.