Taste response to 2,5-anhydro-d-hexitols; rigid stereospecificity of the furanose site in the sugar receptor of the flesh fly

doi:10.1007/BF00615148

Paper

Taste response to 2,5-anhydro-d-hexitols; rigid stereospecificity of the furanose site in the sugar receptor of the flesh fly

Published Oct 1, 1985 · I. Shimada, Hiroyuki Horiki, H. Ohrui

Journal of Comparative Physiology A

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6

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Abstract

Summary2,5-Anhydro-d-mannitol with a fixed furanose ring stimulated the sugar receptor of the flesh fly (Fig. 1) and reacted with the furanose site (Fig. 3). This is the first direct evidence that a furanose can stimulate the sugar receptor and supports strongly the assumption thatβ-d-fructofuranose is the only stimulatory component in the solution ofd-fructose.Rigid stereospecificity of the furanose site in the sugar receptor is discussed according to the effectiveness of various synthetic 2,5-anhydro-d-hexitols and related compounds (Table 2, Fig. 6).At least four receptor sites are concluded to be in a single sugar receptor: a pyranose (P) site, a furanose (F) site, an aliphatic carboxylate (R) site and an aromatic amino acid (Ar) site.

Study Snapshot

A furanose can stimulate the sugar receptor in the flesh fly, supporting the assumption that d-fructose contains only d-fructofuranose as a stimulatory component.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Taste response to 2,5-anhydro-d-hexitols; rigid stereospecificity of the furanose site in the sugar receptor of the flesh fly

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References

Sweet Taste Responses of Fly to Furanoses and their Analogues

The fly's sugar receptors show two distinct responses to sugars, with /?-D-fructofuranose being the most likely structure responsible for its sweet taste.

Stereospecificity of multiple receptor sites in a labellar sugar receptor of the fleshfly for amino acids and small peptides

The labellar sugar receptor of the fleshfly shows stereospecificity for amino acids and small peptides, with the effectiveness of small peptides mainly dependent on the placement of constituent amino acids rather than their composition.

Sugar reception by an insect water receptor

The water receptor in Protophormia terraenovae's taste hairs efficiently receives sugars, with D-fucose being a better stimulus than water, and the sugar site correlates with water reception ability.

Effect of sugars on the labellar water receptor of the fly

D-fructose, D-fucose, and D-galactose are potent "reactivators" of the fly's water receptor, while other sugars show less or no effect.

Separation of two receptor sites in a single labellar sugar receptor of the flesh-fly by treatment with p-chloromercuribenzoate.

Two distinct sugar receptor sites in the fly's flesh-fly brain have been identified, with p-chloromercuribenzoate affecting d-glucose response but not d-fructose response.

Sugar receptor specificity in the fleshfly, Sarcophaga bullata.

Sarcophaga bullata's sweet receptor is most responsive to d-pyranosides and myo-inositol, with some anomalous actions observed.

The Effects of Amino Acids on the Labellar Hair Chemosensory Cells of the Fly

Amino acids in four main classes affect fly labellar hair chemosensory cells, affecting salt, sugar, and protein receptors.

The distribution and neuroanatomy of the labellar sense organs of the blowfly Phormia regina Meigen

The labellar sense organs of Phormia regina Meigen's blowfly are arranged in a definite pattern, with variable number and position of hairs and interpseudotracheal papillae.

Generator Potential of Insect Chemoreceptor

Insect chemosensory hairs show depolarization when stimulated by sucrose or NaCl, but hyperpolarization when stimulated by CaCl2, quinine, and acetic acid.

Citations

The Regulation Index: A New Method for Assessing the Relationship between Oxygen Consumption and Environmental Oxygen

The regulation index (RI) is a new method for assessing the relationship between oxygen consumption and environmental oxygen, providing a clearer definition of the response to environmental oxygen pressure.

Mechanisms of gustatory coding in Spodoptera littoralis

Taste sensilla on the antennae of Spodoptera littoralis respond to sugars and NaCl, but not bitter compounds or amino acids, and have four distinct projection areas in the brain.

The labellar sugar receptor ofDrosophila

The sugar receptor in Drosophila's taste hairs shows similarities to calyptrate flies', but the number of receptor sites may be greater than previously thought, suggesting a mosaic of highly specific sites.

Treatment with pronase uncouples water and sugar reception in the lahellar water receptor of the blowfly

Pronase treatment in blowfly taste hairs uncouples water and sugar reception, suggesting the water receptor acts as a typical sugar receptor when water reception is suppressed.

Insect odor and taste receptors.

Insect odor and taste receptors are highly sensitive detectors of food, mates, and oviposition sites, with recent advances in understanding their molecular and cellular basis.