K. Brandt, Z. Jedliński
1985
Citations
0
Influential Citations
10
Citations
Quality indicators
Journal
Macromolecular Chemistry and Physics
Abstract
4,6-Tetrachlorocyclotriphosphazene-2-spiro-2′-dinaphtho [1,2-d:2,1-e] [1,3,2]dioxaphosphepin (1a) and the dinaphtho [2,1-d:1,2-e] derivative (1b) were synthesized and identified on the basis of elemental and spectral (MS, IR, UV, 1H and 31P NMR) analysis. The anticancer activity of the new isomers against P388 leukemia was studied in vivo and discussed in terms of their electronic structures. A strict correlation was found between the resonance effects in the particular isomers and their antitumor activities.