Babak Kaboudin, Khavar Moradi
2006
Citations
0
Influential Citations
17
Citations
Journal
Synthesis
Abstract
A convenient preparative approach for the synthesis of bis[1-diethoxyphosphorylalkyl]amines has been developed. Treatment of aromatic aldehydes with ammonia and reaction with diethyl phosphite gives diethyl aryl[(arylmethylidene)amino]methylphosphonates, which can be easily reacted with diethyl phosphite in the presence of chlorotrimethylsilane to give bis[1-diethoxyphosphorylalkyl]amines. This method is easy, rapid, and good-yielding for the synthesis ofbis[l-diethoxyphosphorylalkyl]amines from simple starting materials.