Update on Parkinson’s Disease Rehabilitation

doi:10.12786/bn.2022.15.e15

Paper

Update on Parkinson’s Disease Rehabilitation

Published Jul 1, 2022 · Seo Yeon Yoon

Brain & NeuroRehabilitation

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Abstract

Parkinson’s disease (PD) is the second most common neurodegenerative disorder. Although dopaminergic drugs are the mainstay for improving PD symptoms, there are still few effective disease-modifying therapies. With the increasing prevalence of PD and the rapid transition to an aging society, more emphasis needs to be placed on rehabilitation that could slow the disease progression combined with pharmacological therapy. In this review, we present an update on evidence related to rehabilitation programs for motor function, swallowing difficulty, and speech disorders in PD. Aerobic exercise, music therapy, dance, virtual reality, and non-invasive brain stimulation have been shown to improve motor function, and telerehabilitation could also be feasibly applied in PD. Recent studies have shown the effectiveness of expiratory muscle strengthening exercises and Lee Silverman Voice Treatment for swallowing difficulty and speech disorders, respectively. Although many rehabilitation programs have been tried, the evidence is still limited. Well-designed future randomized controlled trials with large numbers of participants are needed to establish evidence for rehabilitation in PD.

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Study Snapshot

Key takeawayRehabilitation programs like aerobic exercise, music therapy, and virtual reality can improve motor function and speech disorders in Parkinson's disease.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Update on Parkinson’s Disease Rehabilitation

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References

Citations

Targeting the Sirtuin–1/PPAR–Gamma Axis, RAGE/HMGB1/NF-κB Signaling, and the Mitochondrial Functions by Canagliflozin Augments the Protective Effects of Levodopa/Carbidopa in Rotenone-Induced Parkinson’s Disease

Canagliflozin combined with levodopa/carbidopa may enhance the protective effects of levodopa/carbidopa against rotenone-induced Parkinson's disease.

Association between the length of stay in rehabilitation and mortality among the adults with Parkinson’s disease: 2009–2019 Korean National Health Insurance Service Databases

Longer stays in rehabilitation are associated with a decrease in mortality among Parkinson's disease patients, emphasizing the need for comprehensive and long-term rehabilitation strategies.

The Effectiveness of Inpatient Rehabilitation in Parkinson’s Disease: A Systematic Review of Recent Studies

Inpatient multidisciplinary rehabilitation and non-MR rehabilitation are effective in improving mobility and independence in people with Parkinson's disease, but new study designs are needed for future trials.

Extracellular Vesicles as Biomarkers for Parkinson’s Disease: How Far from Clinical Translation?

Extracellular vesicles show potential as biomarkers for Parkinson's disease, serving as active or involuntary carriers of disease-associated proteins, with potential clinical applications.

Investigating the Impact of Voice Impairment on Quality of Life in Stroke Patients: The Voice Handicap Index (VHI) Questionnaire Study

Stroke patients with voice problems experience reduced quality of life, as assessed by the Voice Handicap Index (VHI), even after controlling for other confounding factors like dysphagia or neurological deficits.