H. H. Zoorob, M. Elsherbini, W. Hamama
May 9, 2012
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Abstract
Ethyl 2-oxocyclododecanecarboxylate (1), and 2-(hydroxyl-methylene)cyclododecanone (7) were used as key intermediates for synthesis of macrocyclic systems incorporating either fused or exocyclic nitrogen heterocycles of differ- ent ring sizes. Ring enlargement was also implemented.