Dexuan Xiang, Yang Yang, Rui Zhang
Oct 4, 2007
Citations
0
Influential Citations
44
Citations
Journal
The Journal of organic chemistry
Abstract
A facile and efficient one-pot synthesis of highly substituted pyridin-2(1H)-ones was developed via Vilsmeier-Haack reactions of readily available enaminones, 2-arylamino-3-acetyl-5,6-dihydro-4H-pyrans, and a mechanism involving sequential ring-opening, haloformylation, and intramolecular nucleophilic cyclization reactions is proposed.