S. Sueki, Ryousuke Takei, Junya Abe
Aug 24, 2011
Citations
0
Influential Citations
16
Citations
Journal
Tetrahedron Letters
Abstract
The reaction of anilines, benzaldehydes, and ethyl 3,3-diethoxypropionate in the presence of Yb(OTf)3 proceeded under mild reaction conditions to give dihydropyridines (DHPs). We have found that the reaction depended on the solvent and the DHPs were obtained selectively in 1,4-dioxane as a solvent. Various 2,6-unsubstituted DHPs were synthesized in one pot in satisfactory yields.