How much Ginkgo Biloba should I take daily?

Research on the daily intake of Ginkgo Biloba suggests varying dosages depending on the desired health outcomes and the duration of the treatment.

A daily dose of 240 mg of Ginkgo biloba extract EGb 761® was found to be effective and safe in improving cognition, psychopathology, functional measures, and quality of life in patients with mild to moderate dementia when administered for 24 weeks .
Studies indicate that doses greater than 200 mg per day, typically 240 mg, administered for at least 22 weeks, show potential benefits over placebo on cognitive performance and activities of daily living in the treatment of dementia.
A lower dose of 120 mg per day of Ginkgo biloba extract was observed to have some effects on activities of daily living and mood in healthy older volunteers, and mild improvements in secondary memory performance in healthy young volunteers.
A dosage regimen of 40 mg twice daily (every 12 hours) of Ginkgo biloba extract was associated with a longer half-life and mean residence time compared to a single 80 mg dose, suggesting a sustained presence in the body, although the higher single dose resulted in a higher peak concentration.
Six-week supplementation with 160 mg/day of Ginkgo biloba extract in physically active young men may provide marginal improvements in endurance performance and blood antioxidant capacity.

In conclusion, the research suggests that a daily dose of 240 mg of Ginkgo biloba extract is effective for treating symptoms of dementia over a period of 22 weeks or longer. Lower doses, such as 120 mg per day, may have some benefits on mood and memory, while a regimen of 40 mg twice daily offers sustained pharmacokinetic effects. For physical performance and antioxidant benefits, a dose of 160 mg/day over six weeks may be beneficial. The specific dosage and duration of Ginkgo biloba intake should be tailored to the individual's health goals and conditions.

How much Ginkgo Biloba should I take daily?

Summary

Sources and full results

Ginkgo biloba extract EGb 761® in dementia with neuropsychiatric features: a randomised, placebo-controlled trial to confirm the efficacy and safety of a daily dose of 240 mg.

A once-daily dose of 240 mg of EGb 761 (Ginkgo biloba extract) is safe and significantly improves cognition, psychopathology, functional measures, and quality of life in patients with mild to moderate dementia and neuropsychiatric symptoms.

Pharmacokinetics and bioavailability of a Ginkgo biloba extract.

A 40 mg twice daily dosage of Ginkgo biloba extract has a longer half-life and mean residence time than a single 80 mg dose, with a maximum concentration time of 2.3 hours after administration.

Effects of Ginkgo biloba on dementia: An overview of systematic reviews.

Ginkgo biloba extract has potential beneficial effects for dementia patients when administered at doses greater than 200mg/day for at least 5 months.

Effects of Six-Week Ginkgo biloba Supplementation on Aerobic Performance, Blood Pro/Antioxidant Balance, and Serum Brain-Derived Neurotrophic Factor in Physically Active Men

Six-week Ginkgo biloba supplementation may marginally improve endurance performance and blood antioxidant capacity, and provide neuroprotection through increased exercise-induced production of BDNF in physically active young men.

The effects of Ginkgo biloba extract (LI 1370) supplementation and discontinuation on activities of daily living and mood in free living older volunteers

Ginkgo biloba extract (GBE) 120 mg/day for 4 months improves daily living activities and mood in healthy older volunteers, but discontinuing treatment may have negative effects.

Modulation of cognitive performance following single doses of 120 mg Ginkgo biloba extract administered to healthy young volunteers

Single doses of 120 mg Ginkgo biloba extract improve secondary memory performance in healthy young volunteers, but have no effect on attention task performance.

Efficacy and Tolerability of a Once Daily Formulation of Ginkgo biloba Extract EGb 761® in Alzheimer’s Disease and Vascular Dementia: Results from a Randomised Controlled Trial

EGb 761®, a once-daily Ginkgo biloba extract, improved cognitive functioning, neuropsychiatric symptoms, and functional abilities in both Alzheimer's disease and vascular dementia patients.

Pharmacokinetic drug interactions involving Ginkgo biloba

Ginkgo biloba leaf extracts (GLEs) may have potential drug interactions, but their safety with synthetic drugs is uncertain at doses up to 240 mg daily.

Proof of efficacy of the Ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia.

Ginkgo biloba special extract EGb 761 is clinically effective and well-tolerated in treating mild to moderate Alzheimer's type and multi-infarct dementia.

Ginkgo biloba extract alleviates oxidative stress and some neurotransmitters changes induced by aluminum chloride in rats.

Ginkgo biloba extract alleviates oxidative stress and neurotransmitter changes induced by aluminum chloride in rats, potentially due to its antioxidant properties.

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