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These studies suggest that trichomoniasis is commonly treated with nitroimidazole drugs like metronidazole and tinidazole, which are effective in achieving parasitological cure, and new treatments, including high-dose regimens and alternative drugs like MTZ-Cl, boric acid, and aminitrozole, are being explored for resistant cases.
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Trichomoniasis, a common sexually transmitted infection caused by the parasite Trichomonas vaginalis, presents challenges in treatment, especially during pregnancy and in cases of drug resistance.
The treatment of trichomoniasis typically involves the use of metronidazole, which is effective in achieving parasitological cure. The inclusion of partner treatment may help prevent reinfection. In cases of drug resistance, alternative therapies such as high-dose metronidazole, tinidazole, and intravaginal boric acid have been used successfully. New derivatives of metronidazole, like MTZ-Cl, are being explored for their efficacy against resistant strains. Importantly, treating trichomoniasis with metronidazole during pregnancy is not associated with an increased risk of preterm birth.
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