10 papers analyzed
These studies suggest the glycocalyx is a dynamic structure crucial for vascular processes, cellular differentiation, and disease progression, including cancer and vascular diseases.
The glycocalyx is a complex and dynamic layer of macromolecules that coats the surface of cells. It plays a crucial role in various cellular functions, including protection, signaling, and interaction with the environment. This synthesis will explore the structure, functions, and significance of the glycocalyx, particularly focusing on its role in vascular health and disease, as well as its implications in cancer progression.
Structure and Composition
Functions in Vascular Health
Role in Disease
Mechanotransduction and Signaling
Therapeutic Implications
The glycocalyx is a multifunctional and dynamic structure that is essential for maintaining cellular and vascular health. Its degradation is linked to various diseases, while its robust presence in cancer cells promotes malignancy. Understanding the glycocalyx's structure and functions opens up potential therapeutic avenues for treating vascular diseases and cancer.
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