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These studies suggest the half-life of caffeine varies significantly across different species and conditions, ranging from 3 hours to over 52 hours.
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Caffeine is a widely consumed stimulant found in various beverages and foods. Understanding its half-life, which is the time it takes for the concentration of caffeine in the blood to reduce by half, is crucial for assessing its effects on different organisms and under various conditions.
General Half-Life in Animals:
Half-Life in Humans:
Half-Life in Infants:
The half-life of caffeine varies significantly across different species and under different physiological conditions. In general, it ranges from a few hours in rabbits to several days in premature infants. In humans, the half-life is typically around 3 hours but can extend to over 10 hours during pregnancy and up to 97.6 hours in neonates. Understanding these variations is essential for tailoring caffeine consumption and therapeutic interventions appropriately.
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