Xiaowei Zhang, Sheng Wang, C. Xi
Jul 23, 2019
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0
Influential Citations
5
Citations
Journal
The Journal of organic chemistry
Abstract
A highly selective monomethylation of 2-arylacetonitrile using CO2 is described. The utilization of trimethyla-mine-borane facilitates the six-electron reduction of CO2. This reaction is the first selective six-electron reductive functionalization of CO2 faciliated by C(sp3)-H bonds. A variety of 2-arylpropionitrile was obtained in good yields. The reaction could also be applied at gram scale.