Eul‐Soo Park, Joo‐Young Dong, J. Shin
Sep 25, 2013
Citations
3
Influential Citations
61
Citations
Journal
Organic & biomolecular chemistry
Abstract
Isopropylamine is an ideal amino donor for reductive amination of carbonyl compounds by ω-transaminase (ω-TA) owing to its cheapness and high volatility of a ketone product. Here we developed asymmetric synthesis of unnatural amino acids via ω-TA-catalyzed amino group transfer between α-keto acids and isopropylamine.