P. Bharadwaj, W. Musker
May 1, 1987
Citations
0
Influential Citations
19
Citations
Journal
Inorganic Chemistry
Abstract
2-Aminocyclopent-1-ene-1-dithiocarboxylic acid (ACDA), a compound having antifungal properties, forms complexes with transition metals (Ni(II), Pt(II), Pd(II), Mo(VI)) that were believed to be monomeric, neutral species with S,S rather than N,S bonding to the metal. However, no crystallographic information on any of these complexes was obtained because of their limited solubility in common organic solvents. However, it is easy to derivatize the amine group of the ligand by transamination reactions to give species having a variety of substituents at the nitrogen atom. These derivative give complexes with improved solubility characteristics. As part of a research program to develop a radiopharmaceutical that can bind strongly to both Pb(II) and Bi(III) and, in addition, have latent functionality to bind to a suitable carrier, the authors have prepared and determined the crystal structure of the Bi(III) complex of 2-(ethylamino)cyclopent-1-ene-1-dithiocarboxylic acid (EACDA). This also appears to be the first crystal structure of a dithiocarboxylate complex with a non transition metal that has been reported.