Y. Sanemitsu, Yoshinori Nakayama, M. Mizutani
Dec 25, 1984
Citations
0
Influential Citations
3
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
Reduction of 3-methylthio-1,2,4-triazin-5(4H)-one (1a) with sodium borohydride afforded 3-methylthio-1,6-dihydrotriazin-5(4H)-one (2b) selectively. 3-Methylthio-6-t-butyl-1,2,4-triazin-5(4H)-one (1d) reacted with sodium borohydride to give mainly 6-t-butyl-2,3-dihydro-1,2,4-triazin-5(4H)-one (3d). The reaction of various 4-methyl-1,2,4-triazin-5(4H)-ones with sodium borohydride and the influence of bulkiness and electronic effect of the substituents at the 3- and 6-positions upon the product ratio, are also discussed.