C. Wan, Ren‐Jie Song, Jin‐Heng Li
Apr 10, 2019
Citations
1
Influential Citations
54
Citations
Journal
Organic letters
Abstract
A simple three-component 1,2-bromoesterification of alkenes with acids and N-bromosuccinimide under electrochemical oxidative conditions is described. This transformation enables the construction of β-bromoalkyl esters via oxidative C-Br/C-O difunctionalization, where a variety of alkenes, including styrenes and cycloolefins, were well tolerated to react efficiently with a wide range of acids, such as aromatic acids, aliphatic acids, and amino acids.