Yi Liu, P. Gao, Junfeng Wang
Apr 1, 2012
Citations
0
Influential Citations
20
Citations
Journal
Synlett
Abstract
1,2-Diaminocyclohexane-hexanedioic acid has been demonstrated to catalyze the asymmetric aldol reactions of cycloketones and various isatin derivatives efficiently in MeOH–H2O. The corresponding products were obtained in good yields (70–90%) with high diastereoselectivity (up to 99:1 anti/syn) and enantioselectivity (up to 99% ee).