M. Helliwell, A. Dinsmore, C. Garner
Feb 15, 1999
Citations
0
Influential Citations
4
Citations
Journal
Acta Crystallographica Section C-crystal Structure Communications
Abstract
The crystal structure of 6-chloro-2-(N,N-dimethyl-aminomethyleneamino)- 1-(pivaloyloxymethyl)pteridin-4-one confirms that the reaction of pterin 8-oxide with acetyl chloride in trifluoroacetic acid produces the 6-chloride, and that the minor product from alkylation of 6-chloro-2-(N,N-dimethylaminomethylene-amino)pteridin-4-one with chloromethyl pivaloate in dimethylformamide with potassium carbonate, is N-1-alkylated and not N-8- or C-4-O-alkylated.