Valérie Martin, H. Molines, C. Wakselman
May 1, 1993
Citations
0
Influential Citations
8
Citations
Journal
Journal of Fluorine Chemistry
Abstract
Abstract A three-step synthesis of 1-bromo-3-trifluoromethylbut-2-ene in 54% overall yield isreported starting from 1,1,1-trifluoroacetone. The electrophilic reactivity of this compoundtowards various nucleophiles has been studied. Thus, for example, condensation withthe sodium salt of diethyl malonate gave ethyl 2-carboethoxy-5-trifluoromethylhex-4-enoate in 66% yield.