Y. Goueffon, G. Montay, F. Roquet
Jan 5, 1981
Citations
0
Influential Citations
4
Citations
Journal
Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie
Abstract
The 1,4-dihydro-1-ethyl-6-fluoro-7-(4-methyl-1-piperazinyl)-4-oxoquinoline- 3-carboxylic acid (1589 R.B.) is a broad antibacterial agent active in experimental infections. The toxicological and pharmacokinetic profiles of the compound administered as methane sulfonic salt (1589 m R.B.), seem to suggest the possibility of using it in systemic infections.