Fátima C Teixeira, Carla Lucas, M. J. M. Curto
Aug 1, 2013
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Journal
Journal of the Brazilian Chemical Society
Abstract
A number of 1H-pyrazolo[3,4-b]pyridine derivatives, starting from 2-chloro-3-formyl pyridine, was synthesized to obtain new 1-hydroxybisphosphonates, a class of compounds with potential biological interest. Spectroscopic data were used to characterize all compounds and to identify N-1 and N-2 regioisomers, and mono-and bisphosphonates derivatives. X-ray diffractometry studies of compound 7a confirmed the proposed structure.