P. Parthiban, V. Ramkumar, Y. Jeong
Dec 19, 2009
Citations
0
Influential Citations
3
Citations
Journal
Acta Crystallographica Section E: Structure Reports Online
Abstract
The crystal structure of the title compound, C21H21F2NO, shows that the compound exists in a twin-chair conformation with an equatorial orientation of the ortho-fluorophenyl groups on either side of the secondary amino group. The title compound is a 1-methylated analog of 2,4-bis(2-fluorophenyl)-3-azabicyclo[3.3.1]nonan-9-one; the two compound both exhibit the same stereochemistry but the orientation of the ortho-fluorophenyl rings differs slightly. In the title compound, the rings are orientated at a dihedral angle of 36.70 (3)° with respect to one another, whereas in the non-methyl analog, the angle is 25.68 (4)°. The crystal structure of the title compound is stabilized by an intermolecular N—H⋯π interaction and a weak C—H⋯F interaction.