P. Babin, B. Bennetau
Jul 30, 2001
Citations
0
Influential Citations
8
Citations
Journal
Tetrahedron Letters
Abstract
Abstract A new class of compounds, 2-alkylidene-benzo[1,3]dioxin-4-ones, have been synthesised by cyclisation of the corresponding o-acyloxy benzoyl chlorides with triethylamine. The 2-methylene-benzo[1,3]dioxin-4-one acts as a prodrug for aspirin and is a useful intermediate in the synthesis of new aspirin prodrugs.