S. M. Ramsh, A. Ivanenko, N. L. Medvedskiy
Aug 1, 2006
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Influential Citations
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Journal
Chemistry of Heterocyclic Compounds
Abstract
It was found that the aminomethylation of 2-amino-5,5-bis(hydroxymethyl)-1,3-thiazol-4(5H)-one and its spiro analogs using primary amines is accompanied by cyclization at the amidine fragment of the molecule with annelation of a tetrahydrotriazine ring. When using secondary amines the aminomethylation occurs at the exocyclic nitrogen atom.