J. Tilley, H. Ramuz, F. Hefti
Dec 1, 1980
Citations
0
Influential Citations
8
Citations
Journal
Journal of medicinal chemistry
Abstract
Starting with 2,6-dichlorophenyl isothiocyanate, 1-(2-aminoethyl)-2-cyano-3-(2,6-dichlorophenyl)guanidine (2) was prepared in three steps. In contrast to the corresponding thiourea 1, this compound was essentially inactive as an antihypertensive agent.