V. A. Artyomov, V. L. Ivanov, A. M. Shestopalov
Sep 29, 1997
Citations
0
Influential Citations
16
Citations
Journal
Tetrahedron
Abstract
Abstract 2-Bromo-1-arylethylidenemalononitriles react with conjugated thiolatonitriles to give products of regioselective S alkylation that can be subsequently involved in the Thorpe reaction. Resulting enaminoacrylonitriles form pyridine ring under base catalysis yielding thienodipyridines. According to this common scheme, functionally substituted thieno[3,2- b ]pyridines, thiazolo[4,5- b ]pyridines, thieno[3,2- b :4,5- b ]dipyridines, their hydrogenated analogues, and pyrido[2′,3′:4,5]thieno[2,3- d ]pyrimidine were synthesized.