Sinenhlanhla N Mthembu, Anamika Sharma, F. Albericio
Nov 27, 2019
Citations
0
Influential Citations
6
Citations
Journal
Organic letters
Abstract
Disulfide-reducing agents play a crucial role in bioconjugate chemistry. Herein, we describe the synthesis of a new disulfide-reducing agent [2-(dibenzylamino)butane-1,4-dithiol (DABDT)] that is conveniently prepared from inexpensive aspartic acid. Being nonmalodorous and highly soluble in a broad range of solvents, DABDT is user-friendly. We have demonstrated its performance both in solution and in the solid phase.