C. Zikos, Nicolas Ferderigos
Mar 14, 1994
Citations
0
Influential Citations
25
Citations
Journal
Tetrahedron Letters
Abstract
Novel trityl type handles have been prepared and applied to solid phase synthesis using 9 - fluorenylmethyloxycarbonyl (Fmoc) for Na - amino protection and acid labile protecting groups for side chain protection. The cleavage of the resultant ester can be carried out by using appropriate mild acidic cocktails 0.1 % (v/v) trifluoroacetic acid, and TFE : CH2Cl2 : CH3COOH 1 : 8 : 1 (v/v).