M. Schubert-Zsilavecz, W. Likussar, D. Gusterhuber
May 1, 1991
Citations
0
Influential Citations
14
Citations
Journal
Monatshefte für Chemie / Chemical Monthly
Abstract
SummaryA new approach to the synthesis of 2H-isoindole-4,7-diones is described. Heating α-amino acids with carbonyl compounds generates azomethine ylides through the elimination of water and carbon dioxide. The ylides were captured by quinones forming 2H-isoindole-4,7-diones, 2,3,3a,7a-tetrahydro-1H-isoindole-4,7-diones and 2,3-dihydro-1H-pyrrolo[2,1-a]isoindole-6,9-diones. The structures were established on the basis of spectroscopy (NMR, mass).