F. Hahn, K. Müllen, U. Schepers
Oct 15, 2008
Citations
0
Influential Citations
2
Citations
Journal
Synlett
Abstract
Here, the versatility of 2-iminothiolane to act as coupling reagent for solid-phase synthesis of polyamine conjugates is shown. This method, which supersedes the use of elaborate protection group strategies, allows the mild coupling of biomacromolecules and other functional moieties. Spermine conjugates with diverse maleimido building blocks were synthesized by a quick and selective reaction.