J. Blake, S. Davies, J. Church
Jan 31, 1986
Citations
0
Influential Citations
7
Citations
Quality indicators
Journal
Pharmacology Biochemistry and Behavior
Abstract
Using electrophoretic application to rat central neurones in vivo, and bath application to frog spinal cord in vitro, 2-methyl-3,3-diphenyl-3-propanolamine was found to be a selective antagonist of N-methyl-DL-aspartate, but not of quisqualate or kainate. In this respect the (-) isomer proved to be about three times more potent than the (+) in both preparations.