F. Sarlo, L. Fabbrini, G. Renzi
1966
Citations
0
Influential Citations
17
Citations
Journal
Tetrahedron
Abstract
Abstract N-methylisoxazolin-5-ones were obtained, in addition to the isomeric 5-methoxy-isoxazoles, by methylation of isoxazolin-5-ones or, through a more direct way, by reaction of N-methylhydroxylamine on β-oxoesters. The structures assigned are proved by catalytic hydrogenation or by alkaline hydrolysis (see next paper). Bromination of both 3-phenyl and 4-phenyl compounds by N-bromosuccinimide is described. Some remarkable differences between physical properties of 3-aryl and 4-aryl compounds in the solid phase are pointed out.