G. Godin, P. Compain, O. Martin
Oct 1, 2003
Citations
1
Influential Citations
1
Citations
Journal
Synlett
Abstract
The use of 2-naphthalenemethyl (NAP) as a versatile amino protecting group is reported. Highly efficient and chemo-selective cleavage of protected tertiary amines using DDQ in CH 2 Cl 2 -MeOH (4:1) has been observed in the presence of various functionalities such as hydroxyl, acetal, alkene, ester, benzyloxy and N-benzyl groups.