M. Loriga, A. Nuvole, G. Paglietti
Jul 1, 1990
Citations
0
Influential Citations
15
Citations
Journal
European Journal of Medicinal Chemistry
Abstract
A certain number of isomeric 2-phenylquinoxalines N-oxides bearing substituents at position 67 were prepared in order to investigate anti-microbial activity. The effect of some electron—withdrawing groups seem to increase an anti-Trichomonas vaginalis activity in vitro. Structure elucidation of 6-acetyl-2-phenylquinoxaline was achieved by an unambiguous synthesis. 1H NMR spectra of N-oxides were examined in detail to establish structure of parent quinoxalines.