Marie-Aimée Plancquaert, M. Redon, Z. Janousek
Mar 18, 1996
Citations
0
Influential Citations
31
Citations
Journal
Tetrahedron
Abstract
Derivatives of 3,3,3-trifluoropropene 1 : alpha-sulfide 2, sulfoxide 3, sulfone 4 and bromide 6 are useful trifluoromethylated synthons. On reaction with diazo compounds, these derivatives can afford trifluoromethyl substituted pyrazolines, pyrazoles, cyclopropanes or allylsulfones in fair to excellent yields. 1,3-Dipolar cycloaddition of trifluoropropene derivatives 2-4 with N-benzylazomethine ylide provides disubstituted 3-trifluoromethyl-pyrrolidines.