Yun He, Baogen Wu, Jun Yang
Oct 16, 2003
Citations
3
Influential Citations
75
Citations
Quality indicators
Journal
Bioorganic & medicinal chemistry letters
Abstract
A series of 2-piperidin-4-yl-benzimidazoles were synthesized and evaluated for antibacterial activities. Certain compounds inhibit bacterial growth with low micromolar minimal inhibitory concentration (MIC). These benzimidazoles are effective against both Gram-positive and Gram-negative bacteria of clinical importance, particularly enterococci, and represent a new class of potential antibacterial agents.