Tone Kristoffersen, J. Hansen
Apr 26, 2017
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Journal
Chemistry of Heterocyclic Compounds
Abstract
A summary of recent synthetic approaches to 3,4-dihydroquinoxalin-2-ones is discussed herein along with highlights of biological activity. The synthetic approaches include access to enantiopure 3,4-dihydroquinoxalin-2-ones from chiral pool amino acids via coupling/cyclization, Michael addition/cyclization cascades, 3,3-disubstituted systems from multicomponent couplings, Bargellini reaction, or photochemical reduction.