E. Oki, S. Oida, Y. Ohashi
May 25, 1974
Citations
0
Influential Citations
17
Citations
Journal
Chemical & pharmaceutical bulletin
Abstract
4β-Methoxy-4α-phenyl-3α, 5α-propanopiperidine derivatives were prepared and tested biologically. Introduction of a m-hydroxy substituent into the phenyl group of these derivatives results in radical potentiation of analgesic and antitussive activities. Also, some N-carbamates of these derivatives exhibit appreciable anti-inflammatory effects with analgesic activity.