S. K. Vashist
Nov 11, 2014
Citations
0
Influential Citations
6
Citations
Journal
Journal of Basic and Applied Sciences
Abstract
During the last three decades, there have been rapidly growing use of 3-aminopropyltriethoxysilane (APTES) in bioanalytical procedures for the development of potential in vitro diagnostics (IVD) [1]. APTES plays a prominent role in the surface modification of bioanalytical platforms [2-10] and the immobilization of biomolecules [11-13]. It is a colorless liquid having a density of 0.946 g mL -1 at 25°C, and melting and boiling points of -70°C and 217°C, respectively. It has been widely used for the development of IVD, especially those based on enzyme-linked immunosorbent assays (ELISA), microgravimetry, surface plasmon resonance (SPR), surface acoustic wave (SAW) and nanomaterials [1]. This manuscript provides an overview of our developed APTES-based bioanalytical procedures and their immense potential for the development of criticallyimproved IVD.