S. Ryabukhin, V. S. Naumchik, A. S. Plaskon
Jun 15, 2011
Citations
0
Influential Citations
40
Citations
Journal
The Journal of organic chemistry
Abstract
A general approach to 3-fluoro-, 3-chloro-, and 3-bromoquinolines which relies on organosilane-promoted Friedländer reaction of α-haloketones is described. The scope of the methylene component as well as influence of the organosilane component on the outcome of the reaction is studied. The method can be used under parallel synthesis conditions.