O. Ribeiro, C. Kirkby, P. Hirom
1986
Citations
0
Influential Citations
1
Citations
Journal
Advances in experimental medicine and biology
Abstract
3-Hydroxybenzo(a)pyrene(3-OH-BP) (I) is a major metabolite of the environmental pro-carcinogen BP. It is produced in a wide variety of biological systems (1–4) and is excreted as a glucuronide in bile (5, 6). Under appropriate conditions it binds to DNA (7) but it is not carcinogenic (8) and is a poor tumour initiator (9).