B. Witczuk, R. A. Khaunina, G. Kupryszewski
Mar 1, 1980
Citations
2
Influential Citations
10
Citations
Quality indicators
Journal
Polish journal of pharmacology and pharmacy
Abstract
Racemic 3-(p-chlorophenyl)-4-aminobutanoic acid was resolved into enantiomers and their absolute configuration determined. Pharmacological activity of hydrochlorides of the racemic acid and its enantiomers has been determined. The R(+) enantiomer was found to be 4.2-9.2-fold as effective as the S(-) one and 1.4-1.9-fold as effective as the racemate.