R. Richards, R. McBride
Apr 1, 1973
Citations
0
Influential Citations
16
Citations
Quality indicators
Journal
Journal of pharmaceutical sciences
Abstract
3-Phenylpropan-1-ol, 2-phenylethanol, and benzyl alcohol were investigated for their inhibitory action against Pseudomonas aeruginosa. 3-Phenylpropan-1-ol was the most effective and benzyl alcohol was the least effective as shown by: (a) growth rate studies using subinhibitory concentrations of the alcohols, (b) determination of minimum inhibitory concentrations, and (c) determination of sterilization times. The three compounds enhance the bactericidal action of benzalkonium chloride against P. aeruginosa in the same ranking order. It is suggested that 3-phenylpropan-1-ol may be a suitable preservative for oral suspensions and mixtures.