A. Kotljarov, R. Irgashev, V. Iaroshenko
Oct 1, 2009
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0
Influential Citations
7
Citations
Journal
Synthesis
Abstract
Reactions of 3-(polyfluoroacyl)chromones and their hetero analogues with a number of 1,3-NCN-dinudeophiles, such as amidines or guanidines, were studied in detail, and preparative access to a set of diverse 5-salicyloyl-4-(polyfluoroalkyl)pyrimidines was elaborated. These compounds appear to be a suitable starting substrates for the synthesis of 4-(polyfluoroalkyl)pyrimidine-5-carboxylic acids or pyrimidines containing a benzofuran-3-yl substituent in the 5-position.