N. Heindel, J. Reid
Jul 1, 1980
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1
Influential Citations
97
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Journal
Journal of Heterocyclic Chemistry
Abstract
The pendant amino and mercapto groups on 4-amino-3-mercapto-4H-4H-1,2,4-triazoles can be cyclized by phenylpropargyl aldehydes. The aldehydes experience Michael addition of the SH to the alkyne linkage and imine formation between the NH2 and the aldehyde carbonyl to produce 3-R-8-aryl-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazepines.